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Zacks Company Profile for Ionis Pharmaceuticals, Inc. (IONS : NSDQ)
 
 • Company Description   
Ionis Pharmaceuticals discovers/develops RNA-targeted therapeutics using its proprietary antisense oligonucleotide technology. Its antisense medicines have been developed/are being developed to treat neurological, cardiovascular and specialty rare diseases.

Number of Employees: 1,069

 
 • Price / Volume Information   
Yesterday's Closing Price: $42.38 Daily Weekly Monthly
20 Day Moving Average: 1,886,882 shares
Shares Outstanding: 159.16 (millions)
Market Capitalization: $6,745.16 (millions)
Beta: 0.23
52 Week High: $52.34
52 Week Low: $23.95
Short Interest Ratio:
  % Price Change % Price Change Relative to S&P 500
4 Week 18.98% 14.52%
12 Week 49.22% 25.52%
Year To Date 21.22% 13.53%
 
 • Address & Contact Information
Street Address Phone / Fax Email Address Web URL
2855 GAZELLE COURT
-
CARLSBAD,CA 92010
USA
ph: 760-931-9200
fax: 760-603-2700
info@ionisph.com http://www.ionispharma.com
 
 • General Corporate Information   
Officers
Brett P. Monia - Chief Executive Officer;Director
Joseph Loscalzo - Chairman of the Board
Elizabeth L. Hougen - Executive Vice President; Finance and Chief Financ
Spencer R. Berthelsen - Director
Allene M. Diaz - Director

Peer Information
Ionis Pharmaceuticals, Inc. (GSAC)
Ionis Pharmaceuticals, Inc. (CASI)
Ionis Pharmaceuticals, Inc. (ALCD.)
Ionis Pharmaceuticals, Inc. (OMNN)
Ionis Pharmaceuticals, Inc. (CGPI.)
Ionis Pharmaceuticals, Inc. (CATX)
Industry / Sector / Ticker Info
Analyst Coverage: No
Industry Group: MED-DRUGS
Sector: Medical
CUSIP: 462222100
SIC: 2834
Fiscal Year
Fiscal Year End: December
Last Reported Quarter: 03/01/25
Next Expected EPS Date: 08/07/25
Share - Related Items
Shares Outstanding: 159.16
Most Recent Split Date: (:1)
Beta: 0.23
Market Capitalization: $6,745.16 (millions)
 
 
 • EPS Information     • Dividend Information
Analyst Coverage: No Dividend Yield: 0.00%
Current Fiscal Quarter EPS Consensus Estimate: $-0.88 Indicated Annual Dividend: $0.00
Current Fiscal Year EPS Consensus Estimate: $-3.13 Payout Ratio:
Number of Estimates in the Fiscal Year Consensus: 11.00 Change In Payout Ratio:
Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00
Next EPS Report Date: 08/07/25  
 

 • Fundamental Ratios
P/E
Current FY Estimate: -
Trailing 12 Months: -
PEG Ratio: -
Price Ratios
Price/Book: 14.18
Price/Cash Flow: -
Price / Sales: 9.39
EPS Growth
vs. Year Ago Period: 5.10%
vs. Previous Quarter: -40.91%
Sales Growth
vs. Year Ago Period: 10.92%
vs. Previous Quarter: -41.85%
ROE
06/30/25 - -
03/31/25 - -91.85
12/31/24 - -100.05
ROA
06/30/25 - -
03/31/25 - -15.77
12/31/24 - -15.70
Current Ratio
06/30/25 - -
03/31/25 - 9.66
12/31/24 - 8.47
Quick Ratio
06/30/25 - -
03/31/25 - 9.62
12/31/24 - 8.43
Operating Margin
06/30/25 - -
03/31/25 - -63.65
12/31/24 - -64.25
Net Margin
06/30/25 - -
03/31/25 - -63.65
12/31/24 - -64.25
Pre-Tax Margin
06/30/25 - -
03/31/25 - -64.65
12/31/24 - -65.25
Book Value
06/30/25 - -
03/31/25 - 2.99
12/31/24 - 3.73
Inventory Turnover
06/30/25 - -
03/31/25 - 0.52
12/31/24 - 0.45
Debt-to-Equity
06/30/25 - -
03/31/25 - 2.63
12/31/24 - 2.12
Debt-to-Capital
06/30/25 - -
03/31/25 - 72.44
12/31/24 - 67.92
 

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