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Zacks Company Profile for Prime Medicine, Inc. (PRME : NSDQ)

• Company Description    Prime Medicine Inc. is a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapies. Prime Medicine Inc. is based in CAMBRIDGE, Mass. Number of Employees: 214

• Price / Volume Information    Yesterday's Closing Price: $4.69 Daily Weekly Monthly 20 Day Moving Average: 4,743,249 shares Shares Outstanding: 134.49 (millions) Market Capitalization: $630.78 (millions) Beta: 2.33 52 Week High: $6.75 52 Week Low: $1.11 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week 221.23% 209.20% 12 Week 278.23% 218.14% Year To Date 60.62% 50.42%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 60 First Street - Cambridge,MA 02141 USA ph: 617-564-0013 fax: - hannah.deresiewicz@sternir.com https://primemedicine.com

• General Corporate Information    Officers Keith Gottesdiener - President; Chief Executive Officer Allan Reine - Chief Financial Officer Carman Alenson - Chief Accounting Officer Thomas Cahill - Director Wendy Chung - Director Peer Information - (-) - (-) - (-) - (-) - (-) - (-) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 74168J101 SIC: 2836 Fiscal Year Fiscal Year End: December Last Reported Quarter: 03/01/25 Next Expected EPS Date: 08/14/25 Share - Related Items Shares Outstanding: 134.49 Most Recent Split Date: (:1) Beta: 2.33 Market Capitalization: $630.78 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-0.29 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-1.30 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 7.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 08/14/25

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 5.75 Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: 9.09% vs. Previous Quarter: -29.03% Sales Growth vs. Year Ago Period: 146.02% vs. Previous Quarter: -33.39% ROE 06/30/25 - - 03/31/25 - -125.05 12/31/24 - -100.07 ROA 06/30/25 - - 03/31/25 - -66.33 12/31/24 - -65.22 Current Ratio 06/30/25 - - 03/31/25 - 4.78 12/31/24 - 5.58 Quick Ratio 06/30/25 - - 03/31/25 - 4.78 12/31/24 - 5.58 Operating Margin 06/30/25 - - 03/31/25 - - 12/31/24 - - Net Margin 06/30/25 - - 03/31/25 - - 12/31/24 - - Pre-Tax Margin 06/30/25 - - 03/31/25 - -5,255.98 12/31/24 - -6,566.61 Book Value 06/30/25 - - 03/31/25 - 0.82 12/31/24 - 1.17 Inventory Turnover 06/30/25 - - 03/31/25 - - 12/31/24 - - Debt-to-Equity 06/30/25 - - 03/31/25 - 0.00 12/31/24 - 0.00 Debt-to-Capital 06/30/25 - - 03/31/25 - 0.00 12/31/24 - 0.00

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