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Zacks Company Profile for Annovis Bio, Inc. (ANVS : NYSE)

• Company Description    Annovis Bio Inc. is a clinical-stage, drug platform company addressing neurodegeneration, such as Alzheimer's disease, Parkinson's disease and Alzheimer's in Down Syndrome. Annovis Bio Inc. is headquartered in Berwyn, Pennsylvania. Number of Employees: 8

• Price / Volume Information    Yesterday's Closing Price: $2.33 Daily Weekly Monthly 20 Day Moving Average: 598,081 shares Shares Outstanding: 19.49 (millions) Market Capitalization: $45.40 (millions) Beta: 1.57 52 Week High: $17.88 52 Week Low: $1.11 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -10.73% -14.01% 12 Week 90.98% 53.54% Year To Date -53.68% -56.04%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 101 Lindenwood Drive Suite 225 - Malvern,PA 19355 USA ph: 484-875-3192 fax: - ir@annovisbio.com http://www.annovisbio.com

• General Corporate Information    Officers Maria Maccecchini - Chief Executive Officer and President Michael Hoffman - Chairman of the Board and Director Claudine Bruck - Director Reid McCarthy - Director Mark White - Director Peer Information - (-) - (-) - (-) - (-) - (-) - (-) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 03615A108 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 03/01/25 Next Expected EPS Date: 08/13/25 Share - Related Items Shares Outstanding: 19.49 Most Recent Split Date: (:1) Beta: 1.57 Market Capitalization: $45.40 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-0.38 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-1.52 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 1.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 08/13/25

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 1.89 Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: 55.56% vs. Previous Quarter: 25.58% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 06/30/25 - - 03/31/25 - -300.56 12/31/24 - -872.99 ROA 06/30/25 - - 03/31/25 - -193.50 12/31/24 - -239.04 Current Ratio 06/30/25 - - 03/31/25 - 10.68 12/31/24 - 3.59 Quick Ratio 06/30/25 - - 03/31/25 - 10.68 12/31/24 - 3.59 Operating Margin 06/30/25 - - 03/31/25 - - 12/31/24 - - Net Margin 06/30/25 - - 03/31/25 - - 12/31/24 - - Pre-Tax Margin 06/30/25 - - 03/31/25 - - 12/31/24 - - Book Value 06/30/25 - - 03/31/25 - 1.23 12/31/24 - 0.67 Inventory Turnover 06/30/25 - - 03/31/25 - - 12/31/24 - - Debt-to-Equity 06/30/25 - - 03/31/25 - 0.00 12/31/24 - 0.00 Debt-to-Capital 06/30/25 - - 03/31/25 - 0.00 12/31/24 - 0.00

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