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Zacks Company Profile for Annovis Bio, Inc. (ANVS : NYSE)

• Company Description    Annovis Bio Inc. is a clinical-stage, drug platform company addressing neurodegeneration, such as Alzheimer's disease, Parkinson's disease and Alzheimer's in Down Syndrome. Annovis Bio Inc. is headquartered in Berwyn, Pennsylvania. Number of Employees: 3

• Price / Volume Information    Yesterday's Closing Price: $9.15 Daily Weekly Monthly 20 Day Moving Average: 38,475 shares Shares Outstanding: 8.16 (millions) Market Capitalization: $74.70 (millions) Beta: 2.11 52 Week High: $28.43 52 Week Low: $8.39 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -21.93% -14.52% 12 Week -36.68% -28.83% Year To Date -47.95% -36.42%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 1055 Westlakes Drive Suite 300 - Berwyn,PA 19312 USA ph: 610-727-3913 fax: - nic.johnson@russopartnersllc.com http://www.annovisbio.com

• General Corporate Information    Officers Maria Maccecchini - President and Chief Executive Officer Michael Hoffman - Chairman of the Board and Director Jeffrey McGroarty - Chief Financial Officer Claudine Bruck - Director Reid McCarthy - Director Peer Information - (-) - (-) - (-) - (-) - (-) - (-) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 03615A108 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 03/01/22 Next Expected EPS Date: 07/27/22 Share - Related Items Shares Outstanding: 8.16 Most Recent Split Date: (:1) Beta: 2.11 Market Capitalization: $74.70 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $ Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-3.02 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 1.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 07/27/22

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 1.78 Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: -56.52% vs. Previous Quarter: -% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 03/31/22 - -37.83 12/31/21 - -40.24 09/30/21 - -38.40 ROA 03/31/22 - -36.86 12/31/21 - -38.86 09/30/21 - -36.96 Current Ratio 03/31/22 - 34.47 12/31/21 - 30.52 09/30/21 - 42.51 Quick Ratio 03/31/22 - 34.47 12/31/21 - 30.52 09/30/21 - 42.51 Operating Margin 03/31/22 - - 12/31/21 - - 09/30/21 - - Net Margin 03/31/22 - - 12/31/21 - - 09/30/21 - - Pre-Tax Margin 03/31/22 - - 12/31/21 - - 09/30/21 - - Book Value 03/31/22 - 5.15 12/31/21 - 5.49 09/30/21 - 5.74 Inventory Turnover 03/31/22 - - 12/31/21 - - 09/30/21 - - Debt-to-Equity 03/31/22 - 0.00 12/31/21 - 0.00 09/30/21 - 0.00 Debt-to-Capital 03/31/22 - 0.00 12/31/21 - 0.00 09/30/21 - 0.00

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