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Zacks Company Profile for Aptose Biosciences, Inc. (APTOF : OTC)

• Company Description    Aptose Biosciences Inc. is a clinical-stage biotechnology company. The company is advancing therapeutics to treat life-threatening cancers, such as acute myeloid leukemia, high-risk myelodysplastic syndromes and other hematologic malignancies. Its lead program APTO-253 has completed a Phase 1 study in patients with solid tumors. Aptose Biosciences Inc., formerly known as Lorus Therapeutics Inc., is headquartered in Toronto, Canada. Number of Employees: 13

• Price / Volume Information    Yesterday's Closing Price: $1.64 Daily Weekly Monthly 20 Day Moving Average: 6,363 shares Shares Outstanding: 2.55 (millions) Market Capitalization: $4.19 (millions) Beta: 0.39 52 Week High: $4.00 52 Week Low: $0.11 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week 15.17% 13.65% 12 Week 32.69% 28.89% Year To Date -75.76% -79.47%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 66 WELLINGTON STREET WEST SUITE 5300 TD BANK TOWER BOX 48 - TORONTO,A6 M5K 1E6 CAN ph: 64-7479-9828 fax: 905-234-2120 ir@aptose.com http://www.aptose.com

• General Corporate Information    Officers William G. Rice - President; Chief Executive Officer and Chairman of Fletcher Payne - Senior Vice President and Chief Financial Officer Denis R. Burger - Director Carol G. Ashe - Director Erich M. Platzer - Director Peer Information - (-) - (-) - (-) - (-) - (-) - (-) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 03835T408 SIC: 2836 Fiscal Year Fiscal Year End: December Last Reported Quarter: 09/01/25 Next Expected EPS Date: 03/27/26 Share - Related Items Shares Outstanding: 2.55 Most Recent Split Date: 2.00 (0.03:1) Beta: 0.39 Market Capitalization: $4.19 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $ Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $ Payout Ratio: Number of Estimates in the Fiscal Year Consensus: Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 03/27/26

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: - Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: 81.91% vs. Previous Quarter: 27.17% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 09/30/25 - - 06/30/25 - - 03/31/25 - - ROA 09/30/25 - -261.38 06/30/25 - -247.69 03/31/25 - -216.18 Current Ratio 09/30/25 - 0.53 06/30/25 - 0.36 03/31/25 - 1.10 Quick Ratio 09/30/25 - 0.53 06/30/25 - 0.36 03/31/25 - 1.10 Operating Margin 09/30/25 - - 06/30/25 - - 03/31/25 - - Net Margin 09/30/25 - - 06/30/25 - - 03/31/25 - - Pre-Tax Margin 09/30/25 - - 06/30/25 - - 03/31/25 - - Book Value 09/30/25 - -7.62 06/30/25 - -5.63 03/31/25 - -3.06 Inventory Turnover 09/30/25 - - 06/30/25 - - 03/31/25 - - Debt-to-Equity 09/30/25 - - 06/30/25 - - 03/31/25 - - Debt-to-Capital 09/30/25 - - 06/30/25 - - 03/31/25 - -

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