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Zacks Company Profile for Crescent Biopharma, Inc. (CBIO : NSDQ)

• Company Description    Crescent Biopharma is a biotechnology company dedicated to advancing novel precision engineered molecules targeting validated biology to advance care for patients with solid tumors. Crescent Biopharma, formerly known as GlycoMimetics Inc., is based in ROCKVILLE, Md. Number of Employees: 44

• Price / Volume Information    Yesterday's Closing Price: $11.04 Daily Weekly Monthly 20 Day Moving Average: 161,681 shares Shares Outstanding: 13.89 (millions) Market Capitalization: $153.37 (millions) Beta: 1.31 52 Week High: $28.77 52 Week Low: $8.72 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -3.75% 0.01% 12 Week -8.61% -4.10% Year To Date -6.91% -3.17%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 300 FIFTH AVENUE - WALTHAM,MA 02451 USA ph: 617-430-5595 fax: 301-738-2137 ir@crescentbiopharma.com http://www.crescentbiopharma.com

• General Corporate Information    Officers Joshua Brumm - Chief Executive Officer and Director Peter Harwin - Chair and Director Jonathan McNeill - Chief Operating Officer and President Richard Scalzo - Chief Financial Officer Alexandra Balcom - Director Peer Information - (-) - (-) - (-) - (-) - (-) - (-) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: G2545C104 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 12/01/25 Next Expected EPS Date: 05/13/26 Share - Related Items Shares Outstanding: 13.89 Most Recent Split Date: 6.00 (0.01:1) Beta: 1.31 Market Capitalization: $153.37 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-0.85 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-3.72 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 6.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 05/13/26

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 0.77 Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: 63.55% vs. Previous Quarter: -215.75% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 12/31/25 - -125.38 09/30/25 - -94.94 06/30/25 - -122.45 ROA 12/31/25 - -104.16 09/30/25 - -66.36 06/30/25 - -76.71 Current Ratio 12/31/25 - 6.56 09/30/25 - 6.63 06/30/25 - 9.21 Quick Ratio 12/31/25 - 6.56 09/30/25 - 6.63 06/30/25 - 9.21 Operating Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Net Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Pre-Tax Margin 12/31/25 - -1,401.16 09/30/25 - - 06/30/25 - - Book Value 12/31/25 - 14.32 09/30/25 - 8.11 06/30/25 - 6.92 Inventory Turnover 12/31/25 - - 09/30/25 - - 06/30/25 - - Debt-to-Equity 12/31/25 - 0.00 09/30/25 - 0.00 06/30/25 - 0.00 Debt-to-Capital 12/31/25 - 0.00 09/30/25 - 0.00 06/30/25 - 0.00

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