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Zacks Company Profile for Lixte Biotechnology Holdings, Inc. (LIXT : NSDQ)

• Company Description    Lixte Biotechnology Holdings Inc. is a drug discovery company which uses biomarker technology to identify enzyme targets associated with serious common diseases. The company's product pipeline is primarily focused on inhibitors of protein phosphatases, used alone and in combination with cytotoxic agents and/or x-ray and immune checkpoint blockers. Lixte Biotechnology Holdings Inc. is based in NY. Number of Employees: 4

• Price / Volume Information    Yesterday's Closing Price: $0.82 Daily Weekly Monthly 20 Day Moving Average: 1,363,940 shares Shares Outstanding: 16.65 (millions) Market Capitalization: $13.70 (millions) Beta: -1.22 52 Week High: $4.12 52 Week Low: $0.77 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -31.43% -22.77% 12 Week -39.50% -33.48% Year To Date -30.86% -15.52%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 680 EAST COLORADO BOULEVARD SUITE 180 - PASADENA,CA 91101 USA ph: 631-830-7092 fax: 631-982-5050 info@lixte.com http://www.lixte.com

• General Corporate Information    Officers John S. Kovach - President and Chief Executive Officer Robert N. Weingarten - Vice President and Chief Financial Officer Philip F. Palmedo - Director Stephen J. Forman - Director Gil N Schwartzberg - Director Peer Information - (-) - (-) - (-) - (-) - (-) - (-) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 539319202 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 03/01/22 Next Expected EPS Date: 08/09/22 Share - Related Items Shares Outstanding: 16.65 Most Recent Split Date: (:1) Beta: -1.22 Market Capitalization: $13.70 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $ Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $ Payout Ratio: Number of Estimates in the Fiscal Year Consensus: Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 08/09/22

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: - Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: 14.29% vs. Previous Quarter: -% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 03/31/22 - -369.68 12/31/21 - -236.51 09/30/21 - -193.29 ROA 03/31/22 - -116.87 12/31/21 - -101.32 09/30/21 - -84.00 Current Ratio 03/31/22 - 6.37 12/31/21 - 16.81 09/30/21 - 24.35 Quick Ratio 03/31/22 - 6.37 12/31/21 - 16.81 09/30/21 - 24.35 Operating Margin 03/31/22 - - 12/31/21 - - 09/30/21 - - Net Margin 03/31/22 - - 12/31/21 - - 09/30/21 - - Pre-Tax Margin 03/31/22 - - 12/31/21 - - 09/30/21 - - Book Value 03/31/22 - 0.00 12/31/21 - 0.09 09/30/21 - 0.19 Inventory Turnover 03/31/22 - - 12/31/21 - - 09/30/21 - - Debt-to-Equity 03/31/22 - - 12/31/21 - 0.00 09/30/21 - 0.00 Debt-to-Capital 03/31/22 - 0.00 12/31/21 - 0.00 09/30/21 - 0.00

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