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Zacks Company Profile for Lexicon Pharmaceuticals, Inc. (LXRX : NSDQ)

• Company Description    Lexicon Genetics Incorporated is a leader in defining the functions of genes for drug discovery using large-scale knockout mouse technology. Lexicon has invented high-throughput gene trapping technology to discover thousands of genes and expand its OmniBank library of tens of thousands of mouse clones. The Company uses an integrated platform of functional genomictechnologies to accelerate large-scale analysis of mammalian gene function for drug discovery. Number of Employees: 103

• Price / Volume Information    Yesterday's Closing Price: $1.15 Daily Weekly Monthly 20 Day Moving Average: 1,651,332 shares Shares Outstanding: 363.40 (millions) Market Capitalization: $417.91 (millions) Beta: 0.71 52 Week High: $1.66 52 Week Low: $0.28 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -17.86% -17.81% 12 Week -19.58% -20.66% Year To Date 55.72% 33.79%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 2445 TECHNOLOGY FOREST BLVD. 11TH FLOOR - THE WOODLANDS,TX 77381 USA ph: 281-863-3000 fax: 281-863-8088 lexinvest@lexpharma.com http://www.lexpharma.com

• General Corporate Information    Officers Michael S. Exton - Chief Executive Officer Raymond Debbane - Chairman Scott M. Coiante - Senior Vice President and Chief Financial Officer Kristen L. Alexander - Vice President; Finance and Accounting Philippe J. Amouyal - Director Peer Information Lexicon Pharmaceuticals, Inc. (CORR.) Lexicon Pharmaceuticals, Inc. (RSPI) Lexicon Pharmaceuticals, Inc. (CGXP) Lexicon Pharmaceuticals, Inc. (BGEN) Lexicon Pharmaceuticals, Inc. (GTBP) Lexicon Pharmaceuticals, Inc. (RGRX) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 528872302 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 09/01/25 Next Expected EPS Date: 03/05/26 Share - Related Items Shares Outstanding: 363.40 Most Recent Split Date: 5.00 (0.14:1) Beta: 0.71 Market Capitalization: $417.91 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-0.07 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-0.17 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 3.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 03/05/26

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 3.48 Price/Cash Flow: - Price / Sales: 5.90 EPS Growth vs. Year Ago Period: 77.78% vs. Previous Quarter: -500.00% Sales Growth vs. Year Ago Period: 710.40% vs. Previous Quarter: -50.87% ROE 12/31/25 - - 09/30/25 - -52.90 06/30/25 - -83.63 ROA 12/31/25 - - 09/30/25 - -26.69 06/30/25 - -42.22 Current Ratio 12/31/25 - - 09/30/25 - 5.64 06/30/25 - 4.16 Quick Ratio 12/31/25 - - 09/30/25 - 5.63 06/30/25 - 4.16 Operating Margin 12/31/25 - - 09/30/25 - -96.77 06/30/25 - -206.43 Net Margin 12/31/25 - - 09/30/25 - -96.77 06/30/25 - -206.43 Pre-Tax Margin 12/31/25 - - 09/30/25 - -96.77 06/30/25 - -206.43 Book Value 12/31/25 - - 09/30/25 - 0.33 06/30/25 - 0.36 Inventory Turnover 12/31/25 - - 09/30/25 - 2.22 06/30/25 - 1.56 Debt-to-Equity 12/31/25 - - 09/30/25 - 0.47 06/30/25 - 0.43 Debt-to-Capital 12/31/25 - - 09/30/25 - 31.99 06/30/25 - 30.24

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