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Zacks Company Profile for Praxis Precision Medicines, Inc. (PRAX : NSDQ)

• Company Description    Praxis Precision Medicines Inc. is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. Praxis Precision Medicines Inc. is based in CAMBRIDGE, Mass. Number of Employees: 116

• Price / Volume Information    Yesterday's Closing Price: $189.99 Daily Weekly Monthly 20 Day Moving Average: 1,273,480 shares Shares Outstanding: 21.17 (millions) Market Capitalization: $4,021.32 (millions) Beta: 2.62 52 Week High: $205.89 52 Week Low: $26.70 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week 350.00% 350.02% 12 Week 220.82% 207.56% Year To Date 146.87% 117.89%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 99 HIGH STREET 30TH FLOOR - BOSTON,MA 02110 USA ph: 617-300-8460 fax: - investors@praxismedicines.com http://www.praxismedicines.com

• General Corporate Information    Officers Marcio Souza - Chief Executive Officer; President and Director Dean Mitchell - Chairman and Director Timothy Kelly - Chief Financial Officer Alex Nemiroff - General Counsel and Corporate Secretary Jeffrey Chodakewitz - Director Peer Information Praxis Precision Medicines, Inc. (CORR.) Praxis Precision Medicines, Inc. (RSPI) Praxis Precision Medicines, Inc. (CGXP) Praxis Precision Medicines, Inc. (BGEN) Praxis Precision Medicines, Inc. (GTBP) Praxis Precision Medicines, Inc. (RGRX) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 74006W207 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 06/01/25 Next Expected EPS Date: 11/05/25 Share - Related Items Shares Outstanding: 21.17 Most Recent Split Date: 11.00 (0.07:1) Beta: 2.62 Market Capitalization: $4,021.32 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-3.41 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-13.44 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 9.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 11/05/25

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 9.57 Price/Cash Flow: - Price / Sales: 470.17 EPS Growth vs. Year Ago Period: -90.23% vs. Previous Quarter: -0.61% Sales Growth vs. Year Ago Period: 1,349.13% vs. Previous Quarter: 2,371.19% ROE 09/30/25 - - 06/30/25 - -60.07 03/31/25 - -50.42 ROA 09/30/25 - - 06/30/25 - -54.84 03/31/25 - -46.74 Current Ratio 09/30/25 - - 06/30/25 - 6.31 03/31/25 - 8.44 Quick Ratio 09/30/25 - - 06/30/25 - 6.31 03/31/25 - 8.44 Operating Margin 09/30/25 - - 06/30/25 - - 03/31/25 - - Net Margin 09/30/25 - - 06/30/25 - - 03/31/25 - - Pre-Tax Margin 09/30/25 - - 06/30/25 - -3,232.61 03/31/25 - -2,617.11 Book Value 09/30/25 - - 06/30/25 - 19.84 03/31/25 - 21.56 Inventory Turnover 09/30/25 - - 06/30/25 - - 03/31/25 - - Debt-to-Equity 09/30/25 - - 06/30/25 - 0.00 03/31/25 - 0.00 Debt-to-Capital 09/30/25 - - 06/30/25 - 0.00 03/31/25 - 0.00

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