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Zacks Company Profile for Praxis Precision Medicines, Inc. (PRAX : NSDQ)

• Company Description    Praxis Precision Medicines Inc. is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. Praxis Precision Medicines Inc. is based in CAMBRIDGE, Mass. Number of Employees: 168

• Price / Volume Information    Yesterday's Closing Price: $320.39 Daily Weekly Monthly 20 Day Moving Average: 432,164 shares Shares Outstanding: 27.85 (millions) Market Capitalization: $8,923.13 (millions) Beta: 2.94 52 Week High: $356.00 52 Week Low: $32.78 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week 7.69% 1.04% 12 Week 5.26% 3.35% Year To Date 8.70% 5.68%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 99 HIGH STREET 30TH FLOOR - BOSTON,MA 02110 USA ph: 617-300-8460 fax: - investors@praxismedicines.com http://www.praxismedicines.com

• General Corporate Information    Officers Marcio Souza - Chief Executive Officer and Director Dean Mitchell - Chairman Timothy Kelly - Chief Financial Officer Lauren Mastrocola - Principal Accounting Officer Stuart Arbuckle - Director Peer Information Praxis Precision Medicines, Inc. (CORR.) Praxis Precision Medicines, Inc. (RSPI) Praxis Precision Medicines, Inc. (CGXP) Praxis Precision Medicines, Inc. (BGEN) Praxis Precision Medicines, Inc. (GTBP) Praxis Precision Medicines, Inc. (RGRX) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 74006W207 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 12/01/25 Next Expected EPS Date: 05/01/26 Share - Related Items Shares Outstanding: 27.85 Most Recent Split Date: 11.00 (0.07:1) Beta: 2.94 Market Capitalization: $8,923.13 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-3.72 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-14.88 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 9.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 05/01/26

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 9.19 Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: -19.05% vs. Previous Quarter: -4.17% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 03/31/26 - - 12/31/25 - -58.74 09/30/25 - -66.90 ROA 03/31/26 - - 12/31/25 - -53.54 09/30/25 - -60.30 Current Ratio 03/31/26 - - 12/31/25 - 10.22 09/30/25 - 5.18 Quick Ratio 03/31/26 - - 12/31/25 - 10.22 09/30/25 - 5.18 Operating Margin 03/31/26 - - 12/31/25 - - 09/30/25 - - Net Margin 03/31/26 - - 12/31/25 - - 09/30/25 - - Pre-Tax Margin 03/31/26 - - 12/31/25 - - 09/30/25 - -3,658.53 Book Value 03/31/26 - - 12/31/25 - 34.85 09/30/25 - 16.23 Inventory Turnover 03/31/26 - - 12/31/25 - - 09/30/25 - - Debt-to-Equity 03/31/26 - - 12/31/25 - 0.00 09/30/25 - 0.00 Debt-to-Capital 03/31/26 - - 12/31/25 - 0.00 09/30/25 - 0.00

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