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Zacks Company Profile for Avidity Biosciences, Inc. (RNA : NSDQ)

• Company Description    Avidity Biosciences Inc. is a biopharmaceutical company pioneering a new class of oligonucleotide-based therapies called Antibody Oligonucleotide Conjugates(TM). The company's AOC platform design, engineer and develop therapeutics which combine the tissue selectivity of monoclonal antibodies and the precision of oligonucleotide therapies. Its lead product candidate consist AOC 1001, is designed to treat myotonic dystrophy type 1,and other muscle programs are focused on the treatment of muscle atrophy, Duchenne muscular dystrophy, facioscapulohumeral muscular dystrophy and Pompe disease. Avidity Biosciences Inc. is based in SAN DIEGO. Number of Employees: 391

• Price / Volume Information    Yesterday's Closing Price: $71.83 Daily Weekly Monthly 20 Day Moving Average: 2,444,093 shares Shares Outstanding: 150.68 (millions) Market Capitalization: $10,823.06 (millions) Beta: 0.90 52 Week High: $71.88 52 Week Low: $21.51 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week 1.40% 0.06% 12 Week 71.80% 66.88% Year To Date 147.01% 109.85%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 10578 SCIENCE CENTER DRIVE SUITE 125 - SAN DIEGO,CA 92121 USA ph: 858-401-7900 fax: - investors@aviditybio.com http://www.aviditybiosciences.com

• General Corporate Information    Officers Sarah Boyce - President; Chief Executive Officer and Director Troy Wilson - Chairman Michael F. MacLean - Chief Financial Officer Carsten Boess - Director Noreen Henig - Director Peer Information Avidity Biosciences, Inc. (CORR.) Avidity Biosciences, Inc. (RSPI) Avidity Biosciences, Inc. (CGXP) Avidity Biosciences, Inc. (BGEN) Avidity Biosciences, Inc. (GTBP) Avidity Biosciences, Inc. (RGRX) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 05370A108 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 09/01/25 Next Expected EPS Date: 02/26/26 Share - Related Items Shares Outstanding: 150.68 Most Recent Split Date: (:1) Beta: 0.90 Market Capitalization: $10,823.06 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-1.11 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-4.45 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 8.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: 1.28% Last Dividend Paid: NA - $0.00 Next EPS Report Date: 02/26/26

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 5.56 Price/Cash Flow: - Price / Sales: 518.64 EPS Growth vs. Year Ago Period: -95.38% vs. Previous Quarter: -4.96% Sales Growth vs. Year Ago Period: 434.03% vs. Previous Quarter: 224.28% ROE 09/30/25 - -37.70 06/30/25 - -33.45 03/31/25 - -26.96 ROA 09/30/25 - -33.70 06/30/25 - -30.22 03/31/25 - -24.57 Current Ratio 09/30/25 - 11.57 06/30/25 - 9.26 03/31/25 - 16.91 Quick Ratio 09/30/25 - 11.57 06/30/25 - 9.26 03/31/25 - 16.91 Operating Margin 09/30/25 - -2,634.59 06/30/25 - -4,247.77 03/31/25 - -4,136.00 Net Margin 09/30/25 - -2,634.59 06/30/25 - -4,247.77 03/31/25 - -4,136.00 Pre-Tax Margin 09/30/25 - -2,634.59 06/30/25 - -4,247.76 03/31/25 - -4,135.99 Book Value 09/30/25 - 12.93 06/30/25 - 9.27 03/31/25 - 11.02 Inventory Turnover 09/30/25 - - 06/30/25 - - 03/31/25 - - Debt-to-Equity 09/30/25 - 0.00 06/30/25 - 0.00 03/31/25 - 0.00 Debt-to-Capital 09/30/25 - 0.00 06/30/25 - 0.00 03/31/25 - 0.00

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