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Zacks Company Profile for Synlogic, Inc. (SYBX : NSDQ)

• Company Description    Synlogic, Inc. engaged in the development of a novel class of living Synthetic Biotic(TM) medicines based on its proprietary drug discovery and development platform. The company's pipeline includes Synthetic Biotic medicines for the treatment of rare genetic diseases such as Urea Cycle Disorder and Phenylketonuria. In addition, the company is leveraging the broad potential of its platform to create Synthetic Biotic medicines for the treatment of other diseases, such as liver disease, inflammatory and immune disorders and cancer. It is collaborating with AbbVie to develop Synthetic Biotic-based treatments for inflammatory bowel disease. Synlogic Inc., formerly known as Mirna Therapeutics Inc., is based in Cambridge, Massachusetts. Number of Employees: 84

• Price / Volume Information    Yesterday's Closing Price: $1.21 Daily Weekly Monthly 20 Day Moving Average: 150,635 shares Shares Outstanding: 70.25 (millions) Market Capitalization: $85.00 (millions) Beta: 1.56 52 Week High: $4.54 52 Week Low: $1.02 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -34.60% -26.33% 12 Week -34.24% -27.70% Year To Date -50.00% -38.91%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 301 Binney St. Suite 402 - Cambridge,MA 02142 USA ph: 617-401-9975 fax: 512-681-5201 dan.rosan@synlogictx.com http://www.synlogictx.com

• General Corporate Information    Officers Aoife Brennan - President and Chief Executive Officer Peter Barrett - Chairman Gregg Beloff - Interim Chief Financial Officer Michael Burgess - Director Michael Heffernan - Director Peer Information Synlogic, Inc. (CORR.) Synlogic, Inc. (RSPI) Synlogic, Inc. (CGXP) Synlogic, Inc. (BGEN) Synlogic, Inc. (GTBP) Synlogic, Inc. (RGRX) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 87166L100 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 03/01/22 Next Expected EPS Date: 08/11/22 Share - Related Items Shares Outstanding: 70.25 Most Recent Split Date: 8.00 (0.14:1) Beta: 1.56 Market Capitalization: $85.00 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-0.29 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-0.90 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 4.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 08/11/22

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 0.64 Price/Cash Flow: - Price / Sales: 42.54 EPS Growth vs. Year Ago Period: 38.89% vs. Previous Quarter: -4.76% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -58.78% ROE 03/31/22 - -43.07 12/31/21 - -44.37 09/30/21 - -46.75 ROA 03/31/22 - -35.97 12/31/21 - -36.82 09/30/21 - -38.31 Current Ratio 03/31/22 - 12.87 12/31/21 - 13.23 09/30/21 - 14.79 Quick Ratio 03/31/22 - 12.87 12/31/21 - 13.23 09/30/21 - 14.79 Operating Margin 03/31/22 - -3,067.42 12/31/21 - - 09/30/21 - - Net Margin 03/31/22 - -3,067.42 12/31/21 - - 09/30/21 - - Pre-Tax Margin 03/31/22 - -3,067.42 12/31/21 - -3,452.74 09/30/21 - -5,168.67 Book Value 03/31/22 - 1.88 12/31/21 - 2.11 09/30/21 - 2.32 Inventory Turnover 03/31/22 - - 12/31/21 - - 09/30/21 - - Debt-to-Equity 03/31/22 - 0.00 12/31/21 - 0.00 09/30/21 - 0.00 Debt-to-Capital 03/31/22 - 0.01 12/31/21 - 0.01 09/30/21 - 0.01

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