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Zacks Company Profile for Vigil Neuroscience, Inc. (VIGL : NSDQ)

• Company Description    Vigil Neuroscience Inc. is a microglia-focused therapeutics company. It focused on developing treatments for both rare and common neurodegenerative diseases by restoring the vigilance of microglia, the sentinel immune cells of the brain. Vigil Neuroscience Inc. is based in CAMBRIDGE, Mass. Number of Employees: 89

• Price / Volume Information    Yesterday's Closing Price: $2.35 Daily Weekly Monthly 20 Day Moving Average: 156,160 shares Shares Outstanding: 49.12 (millions) Market Capitalization: $115.44 (millions) Beta: 1.90 52 Week High: $6.06 52 Week Low: $1.31 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week 57.72% 52.83% 12 Week -12.64% -6.11% Year To Date 38.24% 44.38%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 100 FORGE ROAD SUITE 700 - WATERTOWN,MA 02472 USA ph: 857-254-4445 fax: - lgibson@vigilneuro.com http://www.vigilneuro.com

• General Corporate Information    Officers Ivana Magovcevic-Liebisch - Chief Executive Officer and President Bruce Booth - Chairperson and Director Jennifer Ziolkowski - Chief Financial Officer Cheryl Renee Blanchard - Director Gerhard Koenig - Director Peer Information - (-) - (-) - (-) - (-) - (-) - (-) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 92673K108 SIC: 2836 Fiscal Year Fiscal Year End: December Last Reported Quarter: 03/01/25 Next Expected EPS Date: 08/12/25 Share - Related Items Shares Outstanding: 49.12 Most Recent Split Date: (:1) Beta: 1.90 Market Capitalization: $115.44 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-0.48 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-2.01 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 5.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 08/12/25

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 1.34 Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: 2.00% vs. Previous Quarter: 14.04% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 03/31/25 - -106.00 12/31/24 - -96.50 09/30/24 - -83.89 ROA 03/31/25 - -72.79 12/31/24 - -69.85 09/30/24 - -65.34 Current Ratio 03/31/25 - - 12/31/24 - 2.95 09/30/24 - 3.72 Quick Ratio 03/31/25 - - 12/31/24 - 2.95 09/30/24 - 3.72 Operating Margin 03/31/25 - - 12/31/24 - - 09/30/24 - - Net Margin 03/31/25 - - 12/31/24 - - 09/30/24 - - Pre-Tax Margin 03/31/25 - - 12/31/24 - - 09/30/24 - - Book Value 03/31/25 - - 12/31/24 - 1.75 09/30/24 - 2.23 Inventory Turnover 03/31/25 - - 12/31/24 - - 09/30/24 - - Debt-to-Equity 03/31/25 - - 12/31/24 - 0.00 09/30/24 - 0.00 Debt-to-Capital 03/31/25 - - 12/31/24 - 0.00 09/30/24 - 0.00

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