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Zacks Company Profile for Zymeworks Inc. (ZYME : NSDQ)

• Company Description    Zymeworks Inc. is a clinical-stage biopharmaceutical company. It engages in the discovery, development, and commercialization of bio-therapeutics for the treatment of cancer in Canada. The companys lead product candidate includes ZW25 and ZW33 which are in clinical trial stage. Zymeworks Inc. is headquartered in Vancouver, Canada. Number of Employees: 286

• Price / Volume Information    Yesterday's Closing Price: $23.31 Daily Weekly Monthly 20 Day Moving Average: 544,118 shares Shares Outstanding: 74.84 (millions) Market Capitalization: $1,744.44 (millions) Beta: 1.23 52 Week High: $28.49 52 Week Low: $9.03 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week 0.60% 1.99% 12 Week -11.74% -12.19% Year To Date -11.47% -11.93%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 108 PATRIOT DRIVE SUITE A - MIDDLETOWN,DE 19709 USA ph: 302-274-8744 fax: 604-737-7077 ir@zymeworks.com http://www.zymeworks.com

• General Corporate Information    Officers Kenneth Galbraith - President and Chief Executive Officer;Chair of the Leone Patterson - Executive Vice President; Chief Business and Chief Troy M. Cox - Director Alessandra Cesano - Director Susan Mahony - Director Peer Information Zymeworks Inc. (CORR.) Zymeworks Inc. (RSPI) Zymeworks Inc. (CGXP) Zymeworks Inc. (BGEN) Zymeworks Inc. (GTBP) Zymeworks Inc. (RGRX) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 98985Y108 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 12/01/25 Next Expected EPS Date: 05/14/26 Share - Related Items Shares Outstanding: 74.84 Most Recent Split Date: (:1) Beta: 1.23 Market Capitalization: $1,744.44 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $0.21 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $0.65 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 7.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 05/14/26

• Fundamental Ratios P/E Current FY Estimate: 36.02 Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 5.47 Price/Cash Flow: - Price / Sales: 16.46 EPS Growth vs. Year Ago Period: -77.42% vs. Previous Quarter: -111.54% Sales Growth vs. Year Ago Period: -91.90% vs. Previous Quarter: -90.89% ROE 12/31/25 - -24.85 09/30/25 - -19.25 06/30/25 - -21.59 ROA 12/31/25 - -19.77 09/30/25 - -14.97 06/30/25 - -16.52 Current Ratio 12/31/25 - - 09/30/25 - 6.94 06/30/25 - 7.69 Quick Ratio 12/31/25 - - 09/30/25 - 6.94 06/30/25 - 7.69 Operating Margin 12/31/25 - -76.56 09/30/25 - -47.16 06/30/25 - -59.96 Net Margin 12/31/25 - -76.56 09/30/25 - -47.16 06/30/25 - -59.96 Pre-Tax Margin 12/31/25 - - 09/30/25 - -41.69 06/30/25 - -54.88 Book Value 12/31/25 - - 09/30/25 - 4.26 06/30/25 - 4.80 Inventory Turnover 12/31/25 - - 09/30/25 - - 06/30/25 - - Debt-to-Equity 12/31/25 - - 09/30/25 - 0.00 06/30/25 - 0.00 Debt-to-Capital 12/31/25 - - 09/30/25 - 0.00 06/30/25 - 0.00

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