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Zacks Company Profile for Actuate Therapeutics, Inc. (ACTU : NSDQ)

• Company Description    Actuate Therapeutics Inc. is a clinical stage biopharmaceutical company focused on developing therapies for the treatment of high impact, difficult to treat cancers. The company's lead product includes elraglusib. Actuate Therapeutics Inc. is based in FORT WORTH, Texas. Number of Employees: 10

• Price / Volume Information    Yesterday's Closing Price: $6.12 Daily Weekly Monthly 20 Day Moving Average: 82,439 shares Shares Outstanding: 23.24 (millions) Market Capitalization: $142.25 (millions) Beta: -0.15 52 Week High: $11.99 52 Week Low: $5.47 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -16.74% -16.59% 12 Week -24.35% -25.57% Year To Date 0.00% 0.00%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 1751 RIVER RUN SUITE 400 - FORT WORTH,TX 76107 USA ph: 817-887-8455 fax: - investors@actuatetherapeutics.com https://actuatetherapeutics.com

• General Corporate Information    Officers Daniel M. Schmitt - President; Chief Executive Officer Aaron G.L. Fletcher - Chairperson Paul Lytle - Chief Financial Officer Jason Keyes - Director Roger Sawhney - Director Peer Information - (-) - (-) - (-) - (-) - (-) - (-) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 005083100 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 09/01/25 Next Expected EPS Date: 03/12/26 Share - Related Items Shares Outstanding: 23.24 Most Recent Split Date: (:1) Beta: -0.15 Market Capitalization: $142.25 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-0.23 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-0.99 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 2.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 03/12/26

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 13.01 Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: 54.55% vs. Previous Quarter: 16.67% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 12/31/25 - - 09/30/25 - -2,925.12 06/30/25 - - ROA 12/31/25 - - 09/30/25 - -250.69 06/30/25 - -281.83 Current Ratio 12/31/25 - - 09/30/25 - 2.74 06/30/25 - 0.73 Quick Ratio 12/31/25 - - 09/30/25 - 2.74 06/30/25 - 0.73 Operating Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Net Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Pre-Tax Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Book Value 12/31/25 - - 09/30/25 - 0.47 06/30/25 - -0.13 Inventory Turnover 12/31/25 - - 09/30/25 - - 06/30/25 - - Debt-to-Equity 12/31/25 - - 09/30/25 - 0.00 06/30/25 - - Debt-to-Capital 12/31/25 - - 09/30/25 - 0.00 06/30/25 - -

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