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Zacks Company Profile for Amylyx Pharmaceuticals, Inc. (AMLX : NSDQ)

• Company Description    Amylyx Pharmaceuticals Inc. is a clinical-stage pharmaceutical company. It focuses on developing a novel therapeutic for amyotrophic lateral sclerosis and other neurodegenerative diseases. Amylyx Pharmaceuticals Inc. is based in CAMBRIDGE, Mass. Number of Employees: 123

• Price / Volume Information    Yesterday's Closing Price: $12.08 Daily Weekly Monthly 20 Day Moving Average: 1,456,371 shares Shares Outstanding: 109.82 (millions) Market Capitalization: $1,326.62 (millions) Beta: -0.31 52 Week High: $16.96 52 Week Low: $2.60 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -16.63% -16.49% 12 Week -16.52% -17.86% Year To Date 0.00% 0.00%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 43 Thorndike St. - Cambridge,MA 02141 USA ph: 617-682-0917 fax: - investors@amylyx.com http://www.amylyx.com

• General Corporate Information    Officers Joshua B. Cohen - Co-Chief Executive Officer James M. Frates - Chief Financial Officer Paul Fonteyne - Director Daphne Quimi - Director Karen Firestone - Director Peer Information Amylyx Pharmaceuticals, Inc. (GSAC) Amylyx Pharmaceuticals, Inc. (CASI) Amylyx Pharmaceuticals, Inc. (ALCD.) Amylyx Pharmaceuticals, Inc. (OMNN) Amylyx Pharmaceuticals, Inc. (CGPI.) Amylyx Pharmaceuticals, Inc. (CATX) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-DRUGS Sector: Medical CUSIP: 03237H101 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 09/01/25 Next Expected EPS Date: 03/03/26 Share - Related Items Shares Outstanding: 109.82 Most Recent Split Date: (:1) Beta: -0.31 Market Capitalization: $1,326.62 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-0.40 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-1.22 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 4.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: 65.00% Last Dividend Paid: NA - $0.00 Next EPS Report Date: 03/03/26

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 4.00 Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: 30.19% vs. Previous Quarter: 19.57% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 12/31/25 - - 09/30/25 - -68.95 06/30/25 - -82.48 ROA 12/31/25 - - 09/30/25 - -61.52 06/30/25 - -70.15 Current Ratio 12/31/25 - - 09/30/25 - 13.70 06/30/25 - 8.72 Quick Ratio 12/31/25 - - 09/30/25 - 13.70 06/30/25 - 8.72 Operating Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Net Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Pre-Tax Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Book Value 12/31/25 - - 09/30/25 - 3.02 06/30/25 - 1.88 Inventory Turnover 12/31/25 - - 09/30/25 - - 06/30/25 - - Debt-to-Equity 12/31/25 - - 09/30/25 - 0.00 06/30/25 - 0.00 Debt-to-Capital 12/31/25 - - 09/30/25 - 0.00 06/30/25 - 0.00

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