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Zacks Company Profile for Fulcrum Therapeutics, Inc. (FULC : NSDQ)

• Company Description    Fulcrum Therapeutics Inc. is a clinical-stage biopharmaceutical company. It is focused on genetically defined diseases with an initial focus on rare diseases. Fulcrum Therapeutics Inc. is based in Cambridge, United States. Number of Employees: 45

• Price / Volume Information    Yesterday's Closing Price: $7.63 Daily Weekly Monthly 20 Day Moving Average: 651,999 shares Shares Outstanding: 54.12 (millions) Market Capitalization: $412.92 (millions) Beta: 3.02 52 Week High: $10.11 52 Week Low: $2.32 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -15.13% -17.35% 12 Week 11.88% 7.24% Year To Date 62.34% 41.90%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 26 LANDSDOWNE STREET - CAMBRIDGE,MA 02139 USA ph: 617-651-8851 fax: - kgardner@lifesciadvisors.com http://www.fulcrumtx.com

• General Corporate Information    Officers Alex C. Sapir - President and Chief Executive Officer Kate Haviland - Chairman Alan Musso - Chief Financial Officer Greg Tourangeau - Vice President Sonja Banks - Director Peer Information Fulcrum Therapeutics, Inc. (CORR.) Fulcrum Therapeutics, Inc. (RSPI) Fulcrum Therapeutics, Inc. (CGXP) Fulcrum Therapeutics, Inc. (BGEN) Fulcrum Therapeutics, Inc. (GTBP) Fulcrum Therapeutics, Inc. (RGRX) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 359616109 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 09/01/25 Next Expected EPS Date: 02/24/26 Share - Related Items Shares Outstanding: 54.12 Most Recent Split Date: (:1) Beta: 3.02 Market Capitalization: $412.92 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-0.33 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-1.19 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 7.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: 24.66% Last Dividend Paid: NA - $0.00 Next EPS Report Date: 02/24/26

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 2.08 Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: 11.43% vs. Previous Quarter: -10.71% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 09/30/25 - -32.17 06/30/25 - -31.05 03/31/25 - -0.20 ROA 09/30/25 - -30.04 06/30/25 - -28.96 03/31/25 - -0.19 Current Ratio 09/30/25 - 17.70 06/30/25 - 24.42 03/31/25 - 28.71 Quick Ratio 09/30/25 - 17.70 06/30/25 - 24.42 03/31/25 - 28.71 Operating Margin 09/30/25 - - 06/30/25 - - 03/31/25 - - Net Margin 09/30/25 - - 06/30/25 - - 03/31/25 - - Pre-Tax Margin 09/30/25 - - 06/30/25 - - 03/31/25 - -0.64 Book Value 09/30/25 - 3.67 06/30/25 - 3.96 03/31/25 - 4.23 Inventory Turnover 09/30/25 - - 06/30/25 - - 03/31/25 - - Debt-to-Equity 09/30/25 - 0.00 06/30/25 - 0.00 03/31/25 - 0.00 Debt-to-Capital 09/30/25 - 0.00 06/30/25 - 0.00 03/31/25 - 0.00

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