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Zacks Company Profile for Ionis Pharmaceuticals, Inc. (IONS : NSDQ)
 
 • Company Description   
Ionis Pharmaceuticals discovers/develops RNA-targeted therapeutics using its proprietary antisense oligonucleotide technology. Its antisense medicines have been developed/are being developed to treat neurological, cardiovascular and specialty rare diseases.

Number of Employees: 1,069

 
 • Price / Volume Information   
Yesterday's Closing Price: $63.16 Daily Weekly Monthly
20 Day Moving Average: 3,227,816 shares
Shares Outstanding: 159.39 (millions)
Market Capitalization: $10,067.14 (millions)
Beta: 0.28
52 Week High: $64.72
52 Week Low: $23.95
Short Interest Ratio:
  % Price Change % Price Change Relative to S&P 500
4 Week 47.40% 44.81%
12 Week 70.66% 55.02%
Year To Date 80.66% 63.55%
 
 • Address & Contact Information
Street Address Phone / Fax Email Address Web URL
2855 GAZELLE COURT
-
CARLSBAD,CA 92010
USA
ph: 760-931-9200
fax: 760-603-2700
ir@ionis.com https://ionis.com
 
 • General Corporate Information   
Officers
Brett P. Monia - Chief Executive Officer;Director
Joseph Loscalzo - Chairman of the Board
Elizabeth L. Hougen - Executive Vice President; Finance and Chief Financ
Spencer R. Berthelsen - Director
Allene M. Diaz - Director

Peer Information
Ionis Pharmaceuticals, Inc. (GSAC)
Ionis Pharmaceuticals, Inc. (CASI)
Ionis Pharmaceuticals, Inc. (ALCD.)
Ionis Pharmaceuticals, Inc. (OMNN)
Ionis Pharmaceuticals, Inc. (CGPI.)
Ionis Pharmaceuticals, Inc. (CATX)
Industry / Sector / Ticker Info
Analyst Coverage: No
Industry Group: MED-DRUGS
Sector: Medical
CUSIP: 462222100
SIC: 2834
Fiscal Year
Fiscal Year End: December
Last Reported Quarter: 06/01/25
Next Expected EPS Date: 11/05/25
Share - Related Items
Shares Outstanding: 159.39
Most Recent Split Date: (:1)
Beta: 0.28
Market Capitalization: $10,067.14 (millions)
 
 
 • EPS Information     • Dividend Information
Analyst Coverage: No Dividend Yield: 0.00%
Current Fiscal Quarter EPS Consensus Estimate: $-1.22 Indicated Annual Dividend: $0.00
Current Fiscal Year EPS Consensus Estimate: $-2.66 Payout Ratio:
Number of Estimates in the Fiscal Year Consensus: 13.00 Change In Payout Ratio:
Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00
Next EPS Report Date: 11/05/25  
 

 • Fundamental Ratios
P/E
Current FY Estimate: -
Trailing 12 Months: -
PEG Ratio: -
Price Ratios
Price/Book: 15.94
Price/Cash Flow: -
Price / Sales: 10.65
EPS Growth
vs. Year Ago Period: 255.56%
vs. Previous Quarter: 175.27%
Sales Growth
vs. Year Ago Period: 100.89%
vs. Previous Quarter: 242.42%
ROE
06/30/25 - -45.29
03/31/25 - -91.85
12/31/24 - -100.05
ROA
06/30/25 - -8.99
03/31/25 - -15.77
12/31/24 - -15.70
Current Ratio
06/30/25 - 2.87
03/31/25 - 9.66
12/31/24 - 8.47
Quick Ratio
06/30/25 - 2.86
03/31/25 - 9.62
12/31/24 - 8.43
Operating Margin
06/30/25 - -28.25
03/31/25 - -63.65
12/31/24 - -64.25
Net Margin
06/30/25 - -28.25
03/31/25 - -63.65
12/31/24 - -64.25
Pre-Tax Margin
06/30/25 - -29.04
03/31/25 - -64.65
12/31/24 - -65.25
Book Value
06/30/25 - 3.96
03/31/25 - 2.99
12/31/24 - 3.73
Inventory Turnover
06/30/25 - 0.69
03/31/25 - 0.52
12/31/24 - 0.45
Debt-to-Equity
06/30/25 - 0.99
03/31/25 - 2.63
12/31/24 - 2.12
Debt-to-Capital
06/30/25 - 49.75
03/31/25 - 72.44
12/31/24 - 67.92
 

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