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Zacks Company Profile for Lixte Biotechnology Holdings, Inc. (LIXT : NSDQ)

• Company Description    Lixte Biotechnology Holdings Inc. is a drug discovery company which uses biomarker technology to identify enzyme targets associated with serious common diseases. The company's product pipeline is primarily focused on inhibitors of protein phosphatases, used alone and in combination with cytotoxic agents and/or x-ray and immune checkpoint blockers. Lixte Biotechnology Holdings Inc. is based in NY. Number of Employees: 2

• Price / Volume Information    Yesterday's Closing Price: $3.93 Daily Weekly Monthly 20 Day Moving Average: 74,083 shares Shares Outstanding: 7.48 (millions) Market Capitalization: $29.38 (millions) Beta: 0.94 52 Week High: $6.26 52 Week Low: $0.64 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -7.53% -7.37% 12 Week -18.12% -19.44% Year To Date 0.00% 0.00%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 433 Plaza Real Suite 275 - Boca Raton,FL 33432 USA ph: 631-830-7092 fax: 631-982-5050 pwinvestor@pondel.com http://www.lixte.com

• General Corporate Information    Officers John S. Kovach - Chief Executive Officer and President Robert N. Weingarten - Vice President and Chief Financial Officer Stephen J. Forman - Director Rene Bernards - Director Yun Yen - Director Peer Information - (-) - (-) - (-) - (-) - (-) - (-) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 539319301 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 09/01/25 Next Expected EPS Date: 03/23/26 Share - Related Items Shares Outstanding: 7.48 Most Recent Split Date: 6.00 (0.10:1) Beta: 0.94 Market Capitalization: $29.38 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $ Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $ Payout Ratio: Number of Estimates in the Fiscal Year Consensus: Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 03/23/26

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 9.50 Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: 25.00% vs. Previous Quarter: -13.79% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 12/31/25 - - 09/30/25 - - 06/30/25 - - ROA 12/31/25 - - 09/30/25 - -175.98 06/30/25 - -222.90 Current Ratio 12/31/25 - - 09/30/25 - 10.43 06/30/25 - 1.84 Quick Ratio 12/31/25 - - 09/30/25 - 10.43 06/30/25 - 1.84 Operating Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Net Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Pre-Tax Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Book Value 12/31/25 - - 09/30/25 - 0.41 06/30/25 - 0.24 Inventory Turnover 12/31/25 - - 09/30/25 - - 06/30/25 - - Debt-to-Equity 12/31/25 - - 09/30/25 - 0.00 06/30/25 - 0.00 Debt-to-Capital 12/31/25 - - 09/30/25 - 0.00 06/30/25 - 0.00

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