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Zacks Company Profile for Promis Neurosciences (PMN : NSDQ)

• Company Description    ProMIS Neurosciences Inc. is a development stage biotechnology company. It focused on discovering and developing medicine therapeutics to treat neurodegenerative diseases in particular Alzheimer's disease and amyotrophic lateral sclerosis. The company's product portfolio includes PMN310, PMN350, PMN330, PMN110, PMN120 and PMN130 which are in its pre-clinical stage. ProMIS Neurosciences Inc.is headquartered in Toronto, Canada. Number of Employees: 8

• Price / Volume Information    Yesterday's Closing Price: $0.44 Daily Weekly Monthly 20 Day Moving Average: 3,108,092 shares Shares Outstanding: 51.81 (millions) Market Capitalization: $22.79 (millions) Beta: -0.05 52 Week High: $1.59 52 Week Low: $0.38 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -30.17% -31.40% 12 Week -12.02% -20.08% Year To Date -53.59% -60.62%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL SUITE 200 1920 YONGE STREET - TORONTO,A6 M4S 3E2 CAN ph: 416-847-6898 fax: - katherine.bock@promisneurosciences.com http://www.promisneurosciences.com

• General Corporate Information    Officers Neil Warma - Chief Executive Officer Daniel Geffken - Chief Financial Officer Max Milbury - Vice President Eugene Williams - Director Patrick Kirwin - Director Peer Information - (-) - (-) - (-) - (-) - (-) - (-) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 74346M406 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 06/01/25 Next Expected EPS Date: 11/13/25 Share - Related Items Shares Outstanding: 51.81 Most Recent Split Date: 6.00 (0.02:1) Beta: -0.05 Market Capitalization: $22.79 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-0.15 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-0.45 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 2.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 11/13/25

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: - Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: -123.08% vs. Previous Quarter: -38.10% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 06/30/25 - -266.69 03/31/25 - -186.19 12/31/24 - -198.43 ROA 06/30/25 - -131.59 03/31/25 - -98.56 12/31/24 - -88.43 Current Ratio 06/30/25 - 0.97 03/31/25 - 3.36 12/31/24 - 8.53 Quick Ratio 06/30/25 - 0.97 03/31/25 - 3.36 12/31/24 - 8.53 Operating Margin 06/30/25 - - 03/31/25 - - 12/31/24 - - Net Margin 06/30/25 - - 03/31/25 - - 12/31/24 - - Pre-Tax Margin 06/30/25 - - 03/31/25 - - 12/31/24 - - Book Value 06/30/25 - -0.01 03/31/25 - 0.29 12/31/24 - 0.50 Inventory Turnover 06/30/25 - - 03/31/25 - - 12/31/24 - - Debt-to-Equity 06/30/25 - - 03/31/25 - 0.00 12/31/24 - 0.00 Debt-to-Capital 06/30/25 - - 03/31/25 - 0.00 12/31/24 - 0.00

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