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Zacks Company Profile for Summit Therapeutics PLC (SMMT : NSDQ)

• Company Description    Summit Therapeutics PLC is engaged in the discovery and development of drug to treat the fatal muscle wasting disease Duchenne Muscular Dystrophy and infections caused by the bacteria C. difficile. Summit Therapeutics PLC is headquartered in Abingdon, the United Kingdom. Number of Employees: 159

• Price / Volume Information    Yesterday's Closing Price: $17.49 Daily Weekly Monthly 20 Day Moving Average: 2,017,968 shares Shares Outstanding: 771.15 (millions) Market Capitalization: $13,487.42 (millions) Beta: -1.51 52 Week High: $36.91 52 Week Low: $15.55 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -7.02% -6.86% 12 Week -22.78% -24.03% Year To Date 0.00% 0.00%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 601 BRICKELL KEY DRIVE SUITE 1000 - MIAMI,FL 33131 USA ph: 305-203-2034 fax: 44-12-3544-3999 investors@smmttx.com http://www.smmttx.com

• General Corporate Information    Officers Robert W. Duggan - Co-Chief Executive Officer and Executive Chairman Mahkam Zanganeh - Co-Chief Executive Officer; President and Director Manmeet S. Soni - Chief Operating Officer; Chief Financial Officer a Robert F. Booth - Director Alessandra Cesano - Director Peer Information - (-) - (-) - (-) - (-) - (-) - (-) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-DRUGS Sector: Medical CUSIP: 86627T108 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 09/01/25 Next Expected EPS Date: 02/23/26 Share - Related Items Shares Outstanding: 771.15 Most Recent Split Date: (:1) Beta: -1.51 Market Capitalization: $13,487.42 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-0.32 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $-0.97 Payout Ratio: Number of Estimates in the Fiscal Year Consensus: 4.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 02/23/26

• Fundamental Ratios P/E Current FY Estimate: - Trailing 12 Months: - PEG Ratio: - Price Ratios Price/Book: 70.15 Price/Cash Flow: - Price / Sales: - EPS Growth vs. Year Ago Period: -287.50% vs. Previous Quarter: 59.21% Sales Growth vs. Year Ago Period: -% vs. Previous Quarter: -% ROE 12/31/25 - - 09/30/25 - -311.15 06/30/25 - -208.64 ROA 12/31/25 - - 09/30/25 - -262.35 06/30/25 - -181.28 Current Ratio 12/31/25 - - 09/30/25 - 3.80 06/30/25 - 5.13 Quick Ratio 12/31/25 - - 09/30/25 - 3.80 06/30/25 - 5.13 Operating Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Net Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Pre-Tax Margin 12/31/25 - - 09/30/25 - - 06/30/25 - - Book Value 12/31/25 - - 09/30/25 - 0.26 06/30/25 - 0.35 Inventory Turnover 12/31/25 - - 09/30/25 - - 06/30/25 - - Debt-to-Equity 12/31/25 - - 09/30/25 - 0.00 06/30/25 - 0.00 Debt-to-Capital 12/31/25 - - 09/30/25 - 0.00 06/30/25 - 0.00

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