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Zacks Company Profile for Stoke Therapeutics, Inc. (STOK : NSDQ)

• Company Description    Stoke Therapeutics Inc. is a biopharmaceutical company. It develops antisense oligonucleotide medicines to treat genetic diseases. The company's product candidate consists of STK-001 which is to treat Dravet syndrome, a severe and progressive genetic epilepsy. Stoke Therapeutics Inc. is based in Bedford, Massachusetts. Number of Employees: 128

• Price / Volume Information    Yesterday's Closing Price: $22.86 Daily Weekly Monthly 20 Day Moving Average: 1,376,518 shares Shares Outstanding: 57.12 (millions) Market Capitalization: $1,305.70 (millions) Beta: 1.32 52 Week High: $38.69 52 Week Low: $5.35 Short Interest Ratio:   % Price Change % Price Change Relative to S&P 500 4 Week -24.28% -26.26% 12 Week 25.53% 20.33% Year To Date 107.25% 81.16%

• Address & Contact Information Street Address Phone / Fax Email Address Web URL 45 WIGGINS AVENUE - BEDFORD,MA 01730 USA ph: 781-430-8200 fax: - ir@stoketherapeutics.com http://www.stoketherapeutics.com

• General Corporate Information    Officers Edward M. Kaye - Chief Executive Officer Thomas E. Leggett - Chief Financial Officer Julie A. Smith - Director Adrian R. Krainer - Director Jennifer C. Burstein - Director Peer Information Stoke Therapeutics, Inc. (CORR.) Stoke Therapeutics, Inc. (RSPI) Stoke Therapeutics, Inc. (CGXP) Stoke Therapeutics, Inc. (BGEN) Stoke Therapeutics, Inc. (GTBP) Stoke Therapeutics, Inc. (RGRX) Industry / Sector / Ticker Info Analyst Coverage: No Industry Group: MED-BIOMED/GENE Sector: Medical CUSIP: 86150R107 SIC: 2834 Fiscal Year Fiscal Year End: December Last Reported Quarter: 09/01/25 Next Expected EPS Date: 03/17/26 Share - Related Items Shares Outstanding: 57.12 Most Recent Split Date: (:1) Beta: 1.32 Market Capitalization: $1,305.70 (millions)

• EPS Information     • Dividend Information Analyst Coverage: No Dividend Yield: 0.00% Current Fiscal Quarter EPS Consensus Estimate: $-0.70 Indicated Annual Dividend: $0.00 Current Fiscal Year EPS Consensus Estimate: $0.20 Payout Ratio: 0.00 Number of Estimates in the Fiscal Year Consensus: 7.00 Change In Payout Ratio: Estmated Long-Term EPS Growth Rate: % Last Dividend Paid: NA - $0.00 Next EPS Report Date: 03/17/26

• Fundamental Ratios P/E Current FY Estimate: 115.12 Trailing 12 Months: 34.12 PEG Ratio: - Price Ratios Price/Book: 4.07 Price/Cash Flow: - Price / Sales: 6.35 EPS Growth vs. Year Ago Period: -38.30% vs. Previous Quarter: -62.50% Sales Growth vs. Year Ago Period: 117.25% vs. Previous Quarter: -23.05% ROE 09/30/25 - 13.28 06/30/25 - 18.32 03/31/25 - 19.08 ROA 09/30/25 - 11.40 06/30/25 - 15.48 03/31/25 - 15.72 Current Ratio 09/30/25 - 6.53 06/30/25 - 6.98 03/31/25 - 8.41 Quick Ratio 09/30/25 - 6.53 06/30/25 - 6.98 03/31/25 - 8.41 Operating Margin 09/30/25 - 19.73 06/30/25 - 26.25 03/31/25 - 26.33 Net Margin 09/30/25 - 19.73 06/30/25 - 26.25 03/31/25 - 26.33 Pre-Tax Margin 09/30/25 - 19.73 06/30/25 - 26.90 03/31/25 - 27.00 Book Value 09/30/25 - 5.62 06/30/25 - 6.13 03/31/25 - 6.41 Inventory Turnover 09/30/25 - - 06/30/25 - - 03/31/25 - - Debt-to-Equity 09/30/25 - 0.00 06/30/25 - 0.00 03/31/25 - 0.00 Debt-to-Capital 09/30/25 - 0.00 06/30/25 - 0.00 03/31/25 - 0.00

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